Perioperative Bridging of Anticoagulation - Does Protocol Adherence Improve Outcomes?

Perioperative Bridging Anticoagulation Unhelpful for Invasive Procedures.

Bottom Line Bridging anticoagulation worsens outcomes for patients with atrial fibrillation who undergo an elective invasive procedure, resulting in more episodes of major bleeding and no difference in the rate of stroke or venous thromboembolism. Most of the patients in the study had a CHADS2 score of 1 (23%), 2 (40%), 3 (24%), or 4 (10%). The patients were largely undergoing minor surgical pr...

[Patients with oral anticoagulation--bridging anticoagulation in the perioperative phase].

Oral anticoagulation with a vitamin K-antagonist requires special consideration when surgery or interventional procedures are planned. This is mainly due to the half life of vitamin K-antagonists and to the need for safe and effective anticoagulation prior to and during surgery as well as in the postoperative period. So far, the continuous infusion of unfractionated heparin (UFH) has been the m...

Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation.

BACKGROUND It is uncertain whether bridging anticoagulation is necessary for patients with atrial fibrillation who need an interruption in warfarin treatment for an elective operation or other elective invasive procedure. We hypothesized that forgoing bridging anticoagulation would be noninferior to bridging with low-molecular-weight heparin for the prevention of perioperative arterial thromboe...

Does perioperative local cooling improve immediate outcomes after ambulatory open inguinal hernia repair?

Does tighter perioperative glycemic control improve outcomes for diabetic patients undergoing coronary artery bypass graft surgery?

Background: Patients with diabetes mellitus undergoing coronary artery bypass graft surgery (CABG) have increased perioperative morbidity and mortality. Tighter glycemic control with an insulin infusion immediately after an acute myocardial infarction has been found to reduce mortality among patients with hyperglycemia. It is unknown whether diabetic patients undergoing CABG would also benefit ...